| Gutierrez, J. and Brandan, E. |
A Novel Mechanism of Sequestering FGF-2 by Glypican in Lipid Rafts, Allowing Skeletal Muscle Differentiation.
Mol. Cell. Biol. 30, 1634-1649. Plus Cover Photograph.(2010) |
2010 |
| Hödar C, Assar R, Colombres M, Aravena A, Pavez L, González M, Martínez S, Inestrosa NC, Maass A. |
Genome-wide identification of new Wnt/beta-catenin target genes in the human genome using CART method.
BMC Genomics. 2010 Jun 1;11:348.
|
2010 |
| Medina WT, Laurent S, Brandan E, Aguilera JM. |
Uptake of tritiated liquids by individual breakfast cereal flakes.
J Food Sci. 2010 Apr;75(3):E194-200.
|
2010 |
| Droguett R, Cabello-Verrugio C, Santander C, Brandan E. |
TGF-beta receptors, in a Smad-independent manner, are required for terminal skeletal muscle differentiation.
Exp Cell Res. 2010 Sep 10;316(15):2487-503. Epub 2010 May 13.
|
2010 |
| Ugarte G, Santander C, Brandan E. |
Syndecan-4 and beta1 integrin are regulated by electrical activity in skeletal muscle: Implications for cell adhesion.
Matrix Biol. 2010 Jun;29(5):383-92. Epub 2010 Mar 31.
|
2010 |
| Gutiérrez J, Brandan E. |
A novel mechanism of sequestering fibroblast growth factor 2 by glypican in lipid rafts, allowing skeletal muscle differentiation.
Mol Cell Biol. 2010 Apr;30(7):1634-49. Epub 2010 Jan 25.
|
2010 |
| Cuitino L, Godoy JA, Farías GG, Couve A, Bonansco C, Fuenzalida M, Inestrosa NC. |
Wnt-5a modulates recycling of functional GABAA receptors on hippocampal neurons.
J Neurosci. 2010 Jun 23;30(25):8411-20.
|
2010 |
| de Arce KP, Varela-Nallar L, Farias O, Cifuentes A, Bull P, Couch BA, Koleske AJ, Inestrosa NC, Alvarez AR. |
Synaptic clustering of PSD-95 is regulated by c-Abl through tyrosine phosphorylation.
J Neurosci. 2010 Mar 10;30(10):3728-38.
|
2010 |
| Lazo OM, Mauna JC, Pissani CA, Inestrosa NC, Bronfman FC. |
Axotomy-induced neurotrophic withdrawal causes the loss of phenotypic differentiation and downregulation of NGF signalling, but not death of septal cholinergic neurons.
Mol Neurodegener. 2010 Jan 19;5:5.
|
2010 |
| Dinamarca MC, Sagal JP, Quintanilla RA, Godoy JA, Arrázola MS, Inestrosa NC. |
Amyloid-beta-Acetylcholinesterase complexes potentiate neurodegenerative changes induced by the Abeta peptide. Implications for the pathogenesis of Alzheimer's disease.
Mol Neurodegener. 2010 Jan 18;5:4.
|
2010 |
| Cerpa W, Farías GG, Godoy JA, Fuenzalida M, Bonansco C, Inestrosa NC. |
Wnt-5a occludes Abeta oligomer-induced depression of glutamatergic transmission in hippocampal neurons.
Mol Neurodegener. 2010 Jan 18;5:3.
|
2010 |
| Griffith TN, Varela-Nallar L, Dinamarca MC, Inestrosa NC. |
Neurobiological effects of Hyperforin and its potential in Alzheimer's disease therapy.
Curr Med Chem. 2010;17(5):391-406. Review.
|
2010 |
| Inestrosa NC, Arenas E. |
Emerging roles of Wnts in the adult nervous system.
Nat Rev Neurosci. 2010 Feb;11(2):77-86. Epub 2009 Dec 16. Review. |
2010 |
| Cerpa W, Hancke JL, Morazzoni P, Bombardelli E, Riva A, Marin PP, Inestrosa NC. |
The hyperforin derivative IDN5706 occludes spatial memory impairments and neuropathological changes in a double transgenic Alzheimer's mouse model.
Curr Alzheimer Res. 2010 Mar;7(2):126-33.
|
2010 |
| Parodi J, Sepúlveda FJ, Roa J, Opazo C, Inestrosa NC, Aguayo LG. |
Beta-amyloid causes depletion of synaptic vesicles leading to neurotransmission failure.
J Biol Chem. 2010 Jan 22;285(4):2506-14. Epub 2009 Nov 13.
|
2010 |
| Farías GG, Godoy JA, Cerpa W, Varela-Nallar L, Inestrosa NC. |
Wnt signaling modulates pre- and postsynaptic maturation: therapeutic considerations.
Dev Dyn. 2010 Jan;239(1):94-101. Review. |
2010 |
| Toledo EM, Inestrosa NC. |
Activation of Wnt signaling by lithium and rosiglitazone reduced spatial memory impairment and neurodegeneration in brains of an APPswe/PSEN1DeltaE9 mouse model of Alzheimer's disease.
Mol Psychiatry. 2010 Mar;15(3):272-85, 228. Epub 2009 Jul 21.
|
2010 |
| Carvallo L, Muñoz R, Bustos F, Escobedo N, Carrasco H, Olivares G, Larraín J. |
Non-canonical Wnt signaling induces ubiquitination and degradation of Syndecan4.
J Biol Chem. 2010 Sep 17;285(38):29546-55. Epub 2010 Jul 16.
|
2010 |
| Norambuena A, Metz C, Jung JE, Silva A, Otero C, Cancino J, Retamal C, Valenzuela JC, Soza A, González A. |
Phosphatidic acid induces ligand-independent epidermal growth factor receptor endocytic traffic through PDE4 activation.
Mol Biol Cell. 2010 Aug 15;21(16):2916-29. Epub 2010 Jun 16.
|
2010 |
| Norambuena A, Palma F, Poblete MI, Donoso MV, Pardo E, González A, Huidobro-Toro JP. |
UTP controls cell surface distribution and vasomotor activity of the human P2Y2 receptor through an epidermal growth factor receptor-transregulated mechanism.
J Biol Chem. 2010 Jan 29;285(5):2940-50. Epub 2009 Dec 7.
|
2010 |
| Kenchappa RS, Tep C, Korade Z, Urra S, Bronfman FC, Yoon SO, Carter BD. |
p75 neurotrophin receptor-mediated apoptosis in sympathetic neurons involves a biphasic activation of JNK and up-regulation of tumor necrosis factor-alpha-converting enzyme/ADAM17.
J Biol Chem. 2010 Jun 25;285(26):20358-68. Epub 2010 Apr 26.
|
2010 |
| Lazo OM, Mauna JC, Pissani CA, Inestrosa NC, Bronfman FC. |
Axotomy-induced neurotrophic withdrawal causes the loss of phenotypic differentiation and downregulation of NGF signalling, but not death of septal cholinergic neurons.
Mol Neurodegener. 2010 Jan 19;5:5.
|
2010 |
| Guillemard V, Ivanisevic L, Garcia AG, Scholten V, Lazo OM, Bronfman FC, Saragovi HU. |
An agonistic mAb directed to the TrkC receptor juxtamembrane region defines a trophic hot spot and interactions with p75 coreceptors.
Dev Neurobiol. 2010 Feb 15;70(3):150-64.
|
2010 |
| Huidobro-Toro JP. |
Highlights in basic autonomic neurosciences: nucleotide receptors: molecular signalling and structural elements.
Auton Neurosci. 2010 Aug 18. [Epub ahead of print] No abstract available.
|
2010 |
| Colucci JA, Arita DY, Cunha TS, Di Marco GS, Vio CP, Pacheco-Silva A, Casarini DE. |
Renin-angiotensin system may trigger kidney damage in NOD mice.
J Renin Angiotensin Aldosterone Syst. 2010 Jul 13. [Epub ahead of print]
|
2010 |
| Faunes F, Sanchez N, Castellanos J, Vergara I, Melo F, Larrain J |
Identification of novel transcripts with differential dorso-ventral expression in Xenopus gastrula using serial analysis of gene expression |
2009 |
| Minniti AN, Rebolledo DL, Grez PM, Fadic R, Aldunate R, Volitakis I, Cherny RA, Opazo C, Masters C, Bush AI, Inestrosa NC |
Intracellular amyloid formation in muscle cells of abeta-transgenic Caenorhabditis elegans: determinants and physiological role in copper detoxification. Mol Neurodegener. 2009 Jan 6;4(1):2 |
2009 |
| Inestrosa NC, Dinamarca MC, Alvarez A. |
Amyloid-cholinesterase interactions. Implications for Alzheimer’s disease. FEBS J. 2008 Feb;275(4):625-32. Review. |
0 |
| Dinamarca MC, Colombres M, Cerpa W, Bonansco C, Inestrosa NC. |
Beta-amyloid oligomers affect the structure and function of the postsynaptic region: role of the Wnt signaling pathway.
Neurodegener Dis. 2008;5(3-4):149-52.
|
0 |
| Huidobro-Toro JP, Lorca RA, Coddou C. |
Trace metals in the brain: allosteric modulators of ligand-gated receptor channels, the case of ATP-gated P2X receptors. Eur Biophys J. 2008 Mar;37(3):301-14. |
0 |
| Matus S, Burgos PV, Bravo-Zehnder M, Kraft R, Porras OH, Farías P, Barros LF, Torrealba F, Massardo L, Jacobelli, González A, |
Antiribosomal-P autoantibodies from psychiatric lupus target a novel neuronal surface protein causing calcium influx and apoptosis. J Exp Med. 2007 Dec 24;204 (13):3221-34. |
0 |
| Lee J, Retamal C, Cuitiño L, Caruano-Yzermans A, Shin JE, van Kerkhof P, Marzolo MP, Bu G. |
Adaptor protein sorting nexin 17 regulates amyloid precursor protein trafficking and processing in the early endosomes. J Biol Chem. 2008 Apr 25;283(17):11501-8. |
0 |
| Matthews HK, Marchant L, Carmona-Fontaine C, Kuriyama S, Larraín J, Holt MR, Parsons M, Mayor R. |
Directional migration of neural crest cells in vivo is regulated by Syndecan-4/Rac1 and non-canonical Wnt signaling/RhoA. Development. 2008 May;135(10):1771-80. |
0 |
| Mezzano V, Cabrera D, Vial C, Brandan E. |
Constitutively activated dystrophic muscle fibroblasts show a paradoxical response to TGF-beta and CTGF/CCN2. J Cell Commun Signal. 2007 Dec;1(3-4):205-217. |
0 |
| Vial C, Zúñiga LM, Cabello-Verrugio C, Cañón P, Fadic R, Brandan E. |
Skeletal muscle cells express the profibrotic cytokine connective tissue growth factor (CTGF/CCN2), which induces their dedifferentiation. J Cell Physiol. 2008 May;215(2):410-21. |
0 |
| Cerpa W, Dinamarca MC, Inestrosa NC. |
Structure-function implications in Alzheimer’s disease: effect of Abeta oligomers at central synapses. Curr Alzheimer Res. 2008 Jun;5(3):233-43. |
0 |
| Leisewitz AV, Urrutia CR, Martinez GR, Loyola G, Bronfman M. |
A PPARs cross-talk concertedly commits C6 glioma cells to ligodendrocytes and induces enzymes involved in myelin synthesis. J Cell Physiol. 2008 Jun 9. [Epub ahead of print]
|
0 |
| Alvarez AR, Klein A, Castro J, Cancino GI, Amigo J, Mosqueira M, Vargas LM, Yévenes LF, Bronfman FC, Zanlungo S. |
Imatinib therapy blocks cerebellar apoptosis and improves neurological symptoms in a mouse model of Niemann-Pick type C disease.
FASEB J. 2008 Jun 30. [Epub ahead of print]
|
0 |
| Colombres M, Henríquez JP, Reig GF, Scheu J, Calderón R, Alvarez A, Brandan E, Inestrosa NC. |
Heparin activates Wnt signaling for neuronal morphogenesis. J Cell Physiol. 2008 Sep;216(3):805-15. |
0 |
| Gravotta D, Deora A, Perret E, Oyanadel C, Soza A, Schreiner R, Gonzalez A, Rodriguez-Boulan E. |
AP1B sorts basolateral proteins in recycling and biosynthetic routes of MDCK cells. Proc Natl Acad Sci U S A. 2007 Jan 30;104(5):1564-9. |
0 |
| Gatica A, Aguilera MC, Contador D, Loyola G, Pinto CO, Amigo L, Tichauer JE, Zanlungo S, Bronfman M. |
P450 CYP2C epoxygenase and CYP4A omega-hydroxylase mediate ciprofibrate-induced PPARalpha-dependent peroxisomal proliferation. J Lipid Res. 2007 Apr;48(4):924-34.
|
0 |
| Acuña-Castillo C, Coddou C, Bull P, Brito J, Huidobro-Toro JP. |
Differential role of extracellular histidines in copper, zinc, magnesium and proton modulation of the P2X7 purinergic receptor. J Neurochem. 2007 Apr;101(1):17-26.
|
0 |
| Cabello-Verrugio C, Brandan E. |
A novel modulatory mechanism of transforming growth factor-beta signaling through decorin and LRP-1. J Biol Chem. 2007 Jun 29;282(26):18842-50. |
0 |
| Fuentealba RA, Barría MI, Lee J, Cam J, Araya C, Escudero CA, Inestrosa NC, Bronfman FC, Bu G, Marzolo MP. |
ApoER2 expression increases Abeta production while decreasing Amyloid Precursor Protein (APP) endocytosis: Possible role in the partitioning of APP into lipid rafts and in the regulation of gamma-secretase activity. Mol Neurodegener. 2007 Jul 9;2:14. |
0 |
| Bronfman FC, Escudero CA, Weis J, Kruttgen A. |
Endosomal transport of neurotrophins: roles in signaling and neurodegenerative diseases. Dev Neurobiol. 2007 Aug;67(9):1183-203. Review. |
0 |
| Yuseff MI, Farfan P, Bu G, Marzolo MP. |
A cytoplasmic PPPSP motif determines megalin’s phosphorylation and regulates receptor’s recycling and surface expression. Traffic. 2007 Sep;8(9):1215-30. |
0 |
| Cancino J, Torrealba C, Soza A, Yuseff MI, Gravotta D, Henklein P, Rodriguez-Boulan E, González A. |
Antibody to AP1B adaptor blocks biosynthetic and recycling routes of basolateral proteins at recycling endosomes. Mol Biol Cell. 2007 Dec;18(12):4872-84. |
0 |
| Coddou C, Acuña-Castillo C, Bull P, Huidobro-Toro JP. |
Dissecting the facilitator and inhibitor allosteric metal sites of the P2X4 receptor channel: critical roles of CYS132 for zinc potentiation and ASP138 for copper inhibition. J Biol Chem. 2007 Dec 21;282(51):36879-86. |
0 |
| Fuenzalida K, Quintanilla R, Ramos P, Piderit D, Fuentealba RA, Martinez G, Inestrosa NC, Bronfman M. |
Peroxisome proliferator-activated receptor gamma up-regulates the Bcl-2 anti-apoptotic protein in neurons and induces mitochondrial stabilization and protection against oxidative stress and apoptosis. J Biol Chem. 2007 Dec 21;282(51):37006-15. |
0 |
| Bronfman FC. |
Metalloproteases and gamma-secretase: new membrane partners regulating p75 neurotrophin receptor signaling?. J Neurochem. 2007 Nov;103 Suppl 1:91-100. Review.
|
0 |
| Buvinic S, Bravo-Zehnder M, Boyer JL, Huidobro-Toro JP, González A. |
Nucleotide P2Y1 receptor regulates EGF receptor mitogenic signaling and expression in epithelial cells. J Cell Sci. 2007 Dec 15;120(Pt 24):4289-301. |
0 |
| Gatica A., Aguilera M.C., Contador D., Loyola G., Pinto C.O., Amigo L., Tichauer J.E., Zanlungo S., Bronfman M. |
The cytochromes P450 CYP2C epoxygenase and CYP4A omega-hydroxylase mediate ciprofibrate-induced PPAR alpha-dependent peroxisomal proliferation in isolated rat liver cells. J. Lipid Res. 2007 Apr;48(4):924-34. |
0 |
| Farias G.G., Valles A., Colombres M., Godoy J.A., Toledo E., Lukas R., Barrantes F., Inestrosa N.C. |
Wnt-7a Induces Presynaptic Colocalization of alfa7-Nicotinic Acetylcholine Receptors and Adenomatous Polyposis Coli in Hippocampal Neurons. J. Neurosci. (2007; In Press). |
0 |
| Urra M.S., Escudero C.A., Ramos P., Lisbona M.F., Allende E., Covarrubias P., Parraguez J.I., Zampieri N., Chao M.V., Annaert W., Bronfman F.C. |
TrkA receptor activation by NGF induces shedding of the p75 neurotrophin receptor followed by endosomal gamma -secretase-mediated release of the p75 intracellular domain. J Biol Chem. (2007). |
0 |
| Brandan E., Retamal C., Cabello-Verrugio C., Marzolo M.P. |
The Low density lipoprotein receptor-related protein, LRP, functions as an endocytic receptor for decorin. J. Biol. Chem 281:31562-71 (2006). |
0 |
| Buvinic S., Poblete M.I., Donoso M.V., Delpaino A.M., Briones R., Miranda R., Huidobro-Toro J.P. |
P2Y1 and P2Y2 receptor distribution varies along the human placental vascular tree: role of nucleotides in vascular tone regulation. J Physiol. 573: 427-43 (2006). |
0 |
| Dinamarca M.C., Cerpa W., Garrido J., Hancke J.L., Inestrosa N.C. |
Hyperforin prevents beta-amyloid neurotoxicity and spatial memory impairments by disaggregation of Alzheimer’s amyloid-beta-deposits. MOL. PSYCHIATRY. 11:1032-48 (2006).
|
0 |
| Muñoz R., Moreno M., Oliva C., Orbenes C., Larraín J. |
Syndecan-4 regulates non-canonical Wnt signaling and is essential for convergent and extension movements in Xenopus embryos. Nat. Cell Biol, 8, 492-500 (2006). |
0 |
| Ugarte G., Brandan E. |
Transforming growth factor b signaling is regulated by electrical activity in skeletal muscle cells: TGF-ß type i receptor is transcriptionally up-regulated by myotube excitability. J. Biol. Chem. 28; 18473-14881 (2006). |
0 |
| Cuitino L., Matute R., Retamal C., Inestrosa N.C., Bu G., Marzolo M.P. |
ApoER2 is Endocytosed by a Clathrin-Mediated Process Involving the Adaptor Protein Dab2 Independent of its Rafts’ Association. Traffic 6. 9: 820-838 (2005). |
0 |
| Marzolo M.P., Bu G. |
Morphogens, new passengers on lipoprotein particles Current Opinion in Lipidology (2005). |
0 |
| Quintanilla R.A., Munoz F.J., Metcalfe M.J., Hitschfeld M., Olivares G., Godoy J.A., Inestrosa N.C. |
Trolox and 17beta-estradiol protect against amyloid beta-peptide neurotoxicity by a mechanism that involves modulation of the Wnt signaling pathway. J. Biol Chem. ;280(12), 11615-25 (2005). |
0 |
| Cerpa W., Barria M.I., Chacón M., Suazo M., González M., Opazo C., Bush A.I., Inestrosa N.C. |
The N-Terminal Copper-Binding Domain of the Amyloid Precursor Protein Protects Against Cu2+-Neurotoxicity in vivo. FASEB J. 18, 1701-3 (2004). |
0 |
| Soza A., Fuente E., Norambuena A., Henklein P., González A. |
Sorting competition with membrane-permeable peptides in intact cells revealed discrimination of distinct cytosolic domains in basolateral transmembrane proteins not only at the trans-golgi network but also at pre-golgi stages. J. Biol. Chem. 279; 17376-17383 (2004). |
0 |
| Coddou C., Morales B., González J., Bull P., Garuso M., Rassendren F., Huidobro-Toro J.P. |
Histidine 140 plays a key role in the inhibitory modulation of the P2X4 nucleotide receptor by copper but not zinc. J. Biol. Chem. 278: 36777-85 (2003). |
0 |
| López-Casillas F., Riquelme C., Pérez Y., Ponce-Catañeda V., Osses N., Esparaza López J., González Niñez G., Cabello Verrugio C., Mendoza V., Troncoso V., Brandan E. |
Betaglycan expression is transcriptionally upregulated during skeletal muscle differentiation: Modulation by MyoD and retinoic acid.J. Biol. Chem. 278: 382-390 (2003).
|
0 |
| Opazo C., Huang X., Cherny R.A., Moir R.D., Roher A.E., White A.R., Cappai R., Masters C.L., Tanzi R.E., Inestrosa N.C. and Bush, A. |
Metalloenzyme-like activity of Alzheimer´s disease b-amyloid: Cu-dependent catalytic conversion of dopamine, cholesterol and biological reducing agents to neurotoxic H2O2. J. Biol. Chem. 277:40302-40308 (2002). |
0 |
| Osses N., Brandan E. |
Inhibitors of extracellular matrix formation affect skeletal muscle differentiation via a myogenin-independent mechanism Am. J. Phys. 282, C383-C394 (2002). |
0 |
| Salazar G., González A., |
Novel Mechanism for Regulation of Epidermal Growth Factor Receptor Endocytosis Revealed by Protein Kinase A Inhibition. Mol Biol Cell. 13:1677-1693 (2002). |
0 |
| Bravo-Zehnder M., Orio P., Norambuena A., Wallner M., Meera P., Toro L., Latorre R., and González A. |
Apical sorting of a voltage- and Ca2+-activated K+ channel a-subunit in MDCK cells is independent of N-glycosylation. Proc. Natl. Acad. Sci. USA 97: 13114-13119. (2000). |
0 |
| De Ferrari G.V., Inestrosa N.C. |
Wnt Signaling Function in Alzheimer´s Disease. Brain Res. Reviews 33: 1-12 (2000). |
0 |
| Miranda S., Opazo C., Larrondo L.F., Muñoz F.J., Ruiz F., Leighton F., Inestrosa N.C. |
The role of oxidative stree in the toxicity induced by amyloid b-peptide in Alzheimer´s disease. Prog. Neurobiol. 62: 633-648 (2000). |
0 |
| Farías GG, Alfaro IE, Cerpa W, Grabowski CP, Godoy JA, Bonansco C, Inestrosa NC |
WNT-5a/ JNK signaling promotes the clustering of PSD-95 in hippocampal neurons. J. BIOL. CHEM, 284, 15857-15866, 2009.
|
0 |
| Suazo M, Hodar C, Morgan C, Cerpa W, Cambiazo V, Inestrosa NC, Gonzalez M. |
Overexpression of amyloid precursor protein increases copper content in HEK293 cells. Biochem Biophys Res Commun, 382, 740-4, 2009. |
0 |
| Vázquez M.C., Vargas L.M., Inestrosa N.C., Alvarez A.R. |
c-Abl modulates AICD dependent cellular responses: Transcriptional induction and apoptosis. Journal Cell Physiology, Vol 220, 136–43, 2009.
|
0 |
| Minniti A.N., Rebolledo D.L., Grez P.M., Fadic R., Aldunate R., Volitakis I., Cherny R.A., Opazo C., Masters C., Bush A.I., Inestrosa N.C. |
Intracellular amyloid formation in muscle cells of Abeta-transgenic Caenorhabditis elegans: determinants and physiological role in copper detoxification. Molecular Neurodegeneration, 4(1):2, 2009. |
0 |
| Arrázola M., Varela-Nallar L., Colombres M., Toledo E., Cruzat F., Pavez L., Assar R., Aravena A., González M., Montecinos M, Maass A., Martínez S. and Inestrosa NC. |
Calcium/calmodulin-dependent protein kinase type IV is a target gene of the Wnt/beta-catenin signaling pathway, Journal Cell Physiology, Vol. 221, 658–67, 2009.
|
0 |
| Toledo E.M. and Inestrosa N.C. |
Activation of Wnt signaling by lithium and rosiglitazone reduced spatial memory impairment and neurodegeneration in brains of an APPswe/PSEN1DeltaE9 mouse model of Alzheimer’s disease, Molecular Psyquiatry, 2009.
|
0 |
| Varela-Nallar L., Grabowski C., Alfaro I., Alvarez A. and Inestrosa N.C. |
Role of the Wnt receptor Frizzled-1 presynaptic differentiation and function, Neural Development, 4(1):41. 2009
|
0 |
| Farías G., Godoy J., Cerpa W., Varela-Nallar L. and Inestrosa N.C. |
Wnt signaling modulates pre-and postsynaptic maturation: therapeutic considerations, Developmental Dynamics, 2009
|
0 |
| Minniti A., Cataldo R., Trigo C., Vásquez L., Mujica P., Leigton F., Inestrosa N.C. and Aldunate R. |
Methionine sulfoxide reductase A expression is regulated by the DAF-16/FOXO pathway in Caenorhabditis elegans, Aging Cell, Vol.8, 690-705, 2009.
|
0 |
| Parodi J., Sepulveda F.J., Roa J., Opazo C., Inestrosa N.C., Aguayo L.G. |
(beta) amyloid causes depletion of synaptic vesicles leading to neurotransmission failure. Journal Biological Chemistry, Vol.13, 2009.
|
0 |
| Inestrosa N.C. and Arenas E. |
Emerging roles of Wnts in the adult nervous system. NAT. REV. NEUROSCI. Nature Reviews Neuroscience (a head of print), 2009
|
0 |
| Osses N., Casar J.C., Brandan E. |
Inhibition of extracellular matrix assembly induces the expression of osteogenic markers in skeletal muscle cells by a BMP-2 independent mechanism. BMC Cell Biology, Oct-73, 2009. |
0 |
| Droppelmann C.A., Gutiérrez J., Vial C., Brandan E. |
Matrix metalloproteinase-2-deficient fibroblasts exhibit an alteration in the fibrotic response to connective tissue growth factor/CCN2 because of an increase in the levels of endogenous fibronectin. Journal Biological Chemistry. 284(20): 13551-61, 2009. |
0 |
| Massardo L., Metz C., Evelin P., Mezzano V., Jarpa E., Babul M., Guzmán, A.M., Sabine, A., Kaltnerf H., Gabius H.J., González A., Soza, A. |
Autoantibodies against galectin-8: Their specificity, association with lymphopenia in systemic lupus erythematosus and detection in rheumatoid arthritis and acute inflammation. Lupus, Ene-00, 539-46, 2009.
|
0 |
| Norambuena A., Palma F., Poblete M.I., Donoso M.V., Pardo E., Gonzalez A., Huidobro-Toro J.P. |
UTP controls cell surface distribution and vasomotor activity of the human P2Y2 receptor through an Epidermal growth factor receptor-transregulated mechanism. Journal Biological Chemistry, Dec 7, 2009.
|
0 |
| Toro, A., Araya C., Córdova G., Arredondo C., Cárdenas H., Moreno R., Venegas A., Koenig C., Cancino J., Gonzalez A., and Santos M |
Pex3p-dependent peroxisomal biogenesis initiates in the endoplasmic reticulum of human fibroblasts. Journal Cell Biochemistry, Vol. 107, 1083-1096, 2009.
|
0 |
| Gonzalez A. and Rodriguez-Boulan E. |
Clathrin and AP1B: Key roles in basolateral trafficking and transendosomal routes. FEBS Letters. Special Issue “The Golgi Complex”, Vol.583, 3784-3795, 2009.
|
0 |
| Norambuena, A., Metz C., Vicuña L., Silva A., Pardo E., Oyanadel C., González A., Soza A. |
Galectin-8 induces apoptosis in jurkat t cells by phosphatidic acid-mediated erk 1/2 activation supported by PKA down regulation. Journal Biological Chemistry, Vol.284, 12670-9, 2009.
|
0 |
| Coddou C., Codocedo J.F., Li S., Lillo J.G., Acuña-Castillo C., Bull P., Stojilkovic S.S., Huidobro-Toro J.P. |
Reactive oxygen species potentiate the P2X2 receptor activity through intracellular Cys430. Journal Neuroscience. 29(39):12284-91. 2009.
|
0 |
| Rivas-Aravena A., Ramdohr P., Vallejos M., Valiente-Echeverría F., Dormoy-Raclet V., Rodríguez F., Pino K., Holzmann C., Huidobro-Toro J.P., Gallouzi I.E., López-Lastra M. |
The Elav-like protein HuR exerts translational control of viral internal ribosome entry sites. Virology, 392(2):178-85, 2009.
|
0 |
| Codocedo J.F., Rodríguez F.E., Huidobro-Toro J.P. |
Neurosteroids differentially modulate P2X ATP-gated channels through non-genomic interactions. Journal Neurochemistry, 110(2):734-44, 2009.
|
0 |
| Figueroa X.F., Poblete I., Fernández R., Pedemonte C., Cortés V., Huidobro-Toro J.P. |
NO production and eNOS phosphorylation induced by epinephrine through the activation of beta-adrenoceptors.
American Journal of Physiology Heart and Circulatory Physiology, 297(1): H134-43, 2009.
|
0 |
| Buvinic S., Almarza G., Bustamante M., Casas M., Lopez J., Riquelme M., Saez J.C., Huidobro-Toro J.P., Jaimovich E. |
ATP released by electrical stimuli elicits calcium transients in skeletal muscle. Journal Biological Chemistry, Oct-12, 2009.
|
0 |
| Vallejos M., Ramdohr P., Valiente-Echeverría F., Tapia K., Rodriguez F.E., Lowy F., Huidobro-Toro J.P., Dangerfield J.A., López-Lastra M. |
The 5'-untranslated region of the mouse mammary tumor virus mRNA exhibits cap-independent translation initiation. Nucleic Acids Research, Nov-04, 2009.
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0 |
| Contreras E.G., Gaete M., Sánchez N., Carrasco H., Larraín J. |
Early requirement of Hyaluronan for tail regeneration in Xenopus tadpoles. Development, 136(17), 2009.
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0 |
| Olivares G.H., Carrasco H., Aroca F., Carvallo L., Segovia F., Larraín J. |
Syndecan-1 regulates BMP signaling and dorso-ventral patterning of the ectoderm during early Xenopus development.
Development Biology, 329(2): 338-49, 2009.
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0 |
| Faunes F., Sánchez N., Castellanos J., Vergara I.A., Melo F., Larraín J. |
Identification of novel transcripts with differential dorso-ventral expression in Xenopus gastrula using serial analysis of gene expression. Genome Biology, 11;10(2), R15. [Epub ahead of print], 2009.
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0 |
| Donoso M., Retamal D., Bu G., Lee J., Van Kerkhof P., Cancino J., Gonzalez A., Cáceres A., Marzolo M.P. |
Different Y-dependent signals direct basolateral sorting of LRP in the secretory and recycling pathways. Molecular Biology Cell, Jan;20(1): 481-97, 2009. |
0 |
| Marzolo M.P. and Bu G. |
Lipoprotein receptors and cholesterol in APP trafficking and proteolytic processing, implications for Alzheimer's disease. Seminars in Cell and Developmental Biology, Apr;20(2), 191-200, 2009.
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0 |
| Cabezas F., Ramos B., Céspedes C., Vio C.P., Bronfman M. and Marzolo M.P. |
Megalin/LRP2 Expression is induced by peroxisome proliferator-activated receptor-alpha and –gamma: Physiopathological implications for kidney function. Kidney International, 2009.
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0 |
| Guillemard V., Ivanisevic L., Garcia A.G., Scholten V., Lazo O.M., Bronfman F.C., Saragovi H.U. |
An agonistic mAb directed to the TrkC receptor juxtamembrane region defines a trophic hot spot, and interactions with p75 co-receptors. Developmental Neurobiology, (Epub ahead of print), 2009.
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0 |
| Lazo O.M., Mauna J., Inestrosa N.I., Bronfman F.C. |
Retrograde Neurotrophic signalling support phenotypic differentiation but not survival of Cholinergic septal neurons. Molecular Neurodegeneration Accepted, 2009.
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0 |